Clinical Chemistry Controls
AURORA BIOLABS LLC PD-1/PD-L1 Inhibitor Binding Assay Kit,384 rxn
Immune checkpoint blockade is an important cancer immunotherapy strategy that enhances the immune system’s ability to recognize and destroy tumor cells. The PD-1/PD-L1 signaling pathway is a key immune checkpoint that suppresses T-cell activity and allows cancer cells to evade immune surveillance. Blocking the interaction between PD-1 and PD-L1 can restore immune function and improve anti-tumor responses. The PD-1/PD-L1 Inhibitor Binding Assay is a TR-FRET–based assay designed to quantitatively measure the interaction between PD-1 and PD-L1. In this assay, binding of PD-1 to PD-L1 generates a fluorescence resonance energy transfer (FRET) signal that can be detected by measuring fluorescence emission at 665 nm and 620 nm. Compounds or antibodies that inhibit PD-1/PD-L1 binding reduce the TR-FRET signal, enabling evaluation of potential immune checkpoint inhibitors for cancer research and drug discovery applications.
Meso Scale Discovery R-PLEX Human Cystatin B ASYQP
The R-PLEX Human Cystatin B Assay Kit from Meso Scale Discovery is a multiplex immunoassay for measuring Cystatin B in human serum plasma and other fluids It uses MSD s electrochemiluminescent detection technology offering high sensitivity a broad dynamic range and low sample volume requirements The kit includes a 96-well plate with capture antibodies a detection antibody conjugate calibrator solutions and necessary reagents It detects Cystatin B from 19 pg/mL to 100 000 pg/mL with high specificity
Med Vet International Evencare G2 Hi Lo Glucose Control Solutions, 5mL, (Low 2.5mL, High 2.5mL) 6/Case
EvenCare G2 Blood Glucose System features advanced technology making it easier to care for residents with diabetes. Easy-to-use voice assistance guides you through the testing process and provides you with your results. Minimizes errors and inaccurate results. Fast test time; results in 6 seconds. Small blood requirement, only 1.0uL, means less discomfort. Option to test on the forearm, palm or fingertips. Memory option - stores 300 test times and can provide 7-, 14- and 30-day averaging.
ABclonal Technology Ferritin Heavy Chain Rabbit
This gene encodes the heavy subunit of ferritin the major intracellular iron storage protein in prokaryotes and eukaryotes It is composed of 24 subunits of the heavy and light ferritin chains Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues A major function of ferritin is the storage of iron in a soluble and nontoxic state Defects in ferritin proteins are associated with several neurodegenerative diseases This gene has multiple pseudogenes Several alternatively spliced transcript variants have been observed but their biological validity has not been determined
Cayman Chemical DL-HomocysteIn 1g
An amino acid; inhibits ACh-induced vasodilation of precontracted isolated guinea pig pulmonary artery rings and enhances phenylephrine-induced contraction of isolated guinea pig pulmonary artery rings; inhibits endothelium-dependent ACh-induced vasodilation in the vascular bed of isolated perfused rat pancreas at 200 µM; elevated plasma levels are positively correlated with occlusive arterial diseases and atherosclerosis
Biotium Serum Amyloid A (SAA/2868R), CF740 conjugate, 0.1mg/mL
This antibody reacts with natural and recombinant human Serum Amyloid A (SAA) and does not cross-react with other human cytokines or growth factors. Human SAA proteins are a group of apo-lipoproteins found predominantly in the high-density lipoprotein (HDL) fraction of plasma. SAA is a major acute-phase protein and precursor to amyloid A protein, which is the major constituent of the fibril deposits of reactive amyloidosis. SAA is secreted in large amounts by the liver during microbial infections or inflammatory diseases.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
ONE LAMBDA INC LABScreen Negative Control Serum, 1 Vial, 20 Tests
LABSCREEN NEGATIVE CONTROL SERUM VI=20T
Maine Molecular Quality Controls Inc Xpert FII & FV NOR/ MUT Control
Xpert FII & FV NOR/MUT Control is intended for in vitro use as a quality control to monitor analytical performance of FII & FV detection on the GeneXpert System. Xpert FII & FV NOR/MUT Control is formulated to monitor the detection of mutations Factor II G20210A and Factor V Leiden G1691A, the most common genetic risk factors for thrombotic events. Xpert FII & FV NOR/MUT Control consists of a suspension of synthetic Factor II and Factor V DNA in a proprietary matrix with preservatives. The kit is comprised of four bottles. Two bottles of Xpert FII & FV Normal Control contain wild type Factor II and Factor V DNA. Two bottles of Xpert FII & FV Mutant Control contain homozygous mutant Factor II and Factor V DNA. Xpert FII & FV NOR/MUT Control is comprised of four bottles containing 0.5mL each of synthetic Factor II and Factor V DNA suspended in a non-infectious matrix with carrier DNA, preservatives and stabilizers.
Meso Scale Discovery R-PLEX Mouse SAA ASYQP
The R-PLEX Mouse SAA Assay from Meso Scale Diagnostics is an electrochemiluminescent immunoassay for the quantitative measurement of serum amyloid A (SAA) in mouse serum plasma and tissue culture supernatants This assay utilizes MSD s proprietary SULFO-TAG labels and multi-array technology to provide a rapid sensitive and reproducible method for measuring SAA levels The assay has a lower limit of detection of 1 3 pg/mL and an upper limit of quantification of 10 000 pg/mL The total assay time is 3 5 hours allowing high-throughput analysis of samples This assay provides a useful tool for studying inflammatory conditions and responses in mouse models of human disease
